Defense Against Toxin Weapons

David R. Franz, DVM, PhD
Colonel, Veterinary Corps
UNITED STATES ARMY

TABLE 2: Comparative Lethality Of Selected Toxins And Chemical

Agents In Laboratory Mice

AGENT

LD50 (mg/kg)

MOLECULAR WEIGHT

SOURCE

Botulinum Toxin

0.001

150,000

Bacterium

Shiga Toxin

0.002

55,000

Bacterium

Tetanus Toxins

0.002

150,000

Bacterium

Abrin

0.04

65,000

Plant (Rosay Pea)

Diptheria Toxin

0.10

62,000

Bacterium

Maitotoxin

0.10

3,400

Marine Dinoflagellate

Palytoxin

0.15

2,700

Marine Soft Coral

Ciguatoxin

0.40

1,000

Fish/Marine Dinoflagellate

Textilotoxin

0.60

80,000

Elapid Snake

C. perfringens toxins

0.1-5.0

35,000 - 40,000

Bacterium

Batrachotoxin

2.0

539

Attow - Poison Frog

Ricin

3.0

64,000

Plant (Castor-Bean)

Conotoxin

5.0

1,500

Cone Snail

Taipoxin

5.0

46,000

Elapid Snake

Tetrodotoxin

8.0

319

Puffer Fish

aTityustoxin

9.0

8,000

Scorpion

Saxitoxin

10.0 (Inhal;2.0)

299

Marine Dinoflagellate

VX

15.0

267

Chemical Agent

SEB (Rhesus/Aerosol)

27.0 (ED50~pg)

28,494

Bacterium

Anatoxin-A(s)

50.0

500

Blue-Green Alga

Microcystin

50.0

994

Blue-Green Alga

Soman (GD)

64.0

182

Chemical Agent

Sarin (GB)

100.0

140

Chemical Agent

Aconitine

100.0

647

Plant (Monkshood)

T-2 Toxin

1,210.0

466

Fungal Mycotoxin

Source: http://www.usamriid.army.mil/education/defensetox.html

This file's Last Modified Date: November 1, 2001