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THE CONTRYPHANS


Massilia, G.R., Eliseo, T., Grolleau, F., Lapied, B., Barbier, J., Bournaud, R., Molgo, J., Cicero, D.O., Paci, M., Schinina, M.E., Ascenzi, P. and Polticelli, F. (2003) Contryphan-Vn: a modulator of Ca2+-dependent K+ channels. Biochem Biophys Res Commun 303:238-246.

Massilia GR, Schinina ME, Ascenzi P and Polticelli F. (2001) Contryphan-Vn: a novel peptide from the venom of the Mediterranean snail Conus ventricosus. Biochem Biophys Res Commun 288:908-913.

Jimenez EC, Watkins M, Juszczak LJ, Cruz LJ and Olivera BM. (2001) Contryphans from Conus textile venom ducts. Toxicon 39:803-808.

Pallaghy PK, He W, Jimenez EC, Olivera BM and Norton RS (2000) Structures of the contryphan family of cyclic peptides. Role of electrostatic interactions in cis-trans isomerism. Biochemistry39:12845-12852.

Pallaghy PK and Norton RS (2000) The cyclic contryphan motif CPxXPXC, a robust scaffold potentially useful as an omega-conotoxin mimic. Biopolymers 54:173-179.

Pallaghy PK, Melnikova AP, Jimenez EC, Olivera BM and Norton RS (1999) Solution structure of contryphan-R, a naturally occurring disulfide-bridged octapeptide containing D-tryptophan: comparison with protein loops. Biochemistry 38:11553-11559.

Jacobsen RB, Jimenez EC, De la Cruz RG, Gray WR, Cruz LJ, Olivera BM (1999) A novel D-leucine-containing Conus peptide: diverse conformational dynamics in the contryphan family. J Pept Res 54:93-99.

England LJ, Imperial J, Jacobsen R, Craig AG, Gulyas J, Akhtar M, Rivier J, Julius D and Olivera BM (1998) Inactivation of a serotonin-gated ion channel by a polypeptide toxin from marine snails. Science 281:575-578. Erratum in: Science 282:417.

Jacobsen R, Jimenez EC, Grilley M, Watkins M, Hillyard D, Cruz LJ and Olivera BM (1998) The contryphans, a D-tryptophan-containing family of Conus peptides: interconversion between conformers. J Pept Res 51:173-179.

Jimenez EC, Craig AG, Watkins M, Hillyard DR, Gray WR, Gulyas J, Rivier JE, Cruz LJ and Olivera BM (1997) Bromocontryphan: post-translational bromination of tryptophan. Biochemistry 36:989-994.

Jimenez EC, Olivera BM, Gray WR and Cruz LJ (1996) Contryphan is a D-tryptophan-containing Conus peptide. J Biol Chem 271:28002-28005.


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